Chemistry Organic Building Blocks Ketones (R)-5-Thia-1-Azabicyclo[4.2.0]Oct-2-En-8-One

(R)-5-Thia-1-Azabicyclo[4.2.0]Oct-2-En-8-One

Nucleophilic Addition: The double bond in the enone moiety of the compound can undergo nucleophilic addition reactions with various nucleophiles, such as amines, alcohols, or thiols. This can result in the formation of new carbon-carbon or carbon-heteroatom bonds. Reductive Reactions: The ketone group in the molecule can be reduced to the corresponding alcohol using reducing agents like sodium borohydride or lithium aluminum hydride. Oxidation: The compound can be oxidized to form various products, depending on the oxidizing agent used. For example, it can be oxidized to form a sulfoxide or sulfone by treatment with appropriate oxidants. Cyclization Reactions: The compound's structure may allow for intramolecular cyclization reactions under specific conditions, leading to the formation of cyclic products. Reaction with Electrophiles: The compound can react with electrophilic reagents or species, such as alkylating agents or acylating agents, resulting in the addition of these groups to the molecule. Rearrangements: Intramolecular rearrangement reactions may take place under certain conditions, leading to the formation of isomeric compounds. Acid-Catalyzed Reactions: In the presence of acid catalysts, various acid-catalyzed reactions can occur, including acylation or hydrolysis reactions.

Further Reading:

Framework+−

(1E,4E)-1,5-Diphenylpenta-1,4-Dien-3-One (1E,6E)-1,7-Diphenylhepta-1,6-Diene-3,5-Dione (2-Aminophenyl)(Phenyl)Methanone (2-Bromophenyl)(Phenyl)Methanone (2-Chlorophenyl)(Phenyl)Methanone (2-Fluorophenyl)(Phenyl)Methanone (2-Hydroxyphenyl)(Phenyl)Methanone (2-Iodophenyl)(Phenyl)Methanone (3-Chlorophenyl)(Phenyl)Methanone (3-Fluorophenyl)(Phenyl)Methanone (3-Nitrophenyl)(Phenyl)Methanone (4-Aminophenyl)(Phenyl)Methanone (4-Bromophenyl)(Phenyl)Methanone (4-Chlorophenyl)(Phenyl)Methanone (4-Fluorophenyl)(Phenyl)Methanone (4-Hydroxyphenyl)(Phenyl)Methanone (4-Methoxyphenyl)(Phenyl)Methanone (4-Nitrophenyl)(Phenyl)Methanone (8S,14R)-6,7,8,9,10,11,12,13,14,15,16,17-Dodecahydro-3H-Cyclopenta[A]Phenanthren-3-One (E)-1-(2-Hydroxyphenyl)-3-Phenylprop-2-En-1-One (R)-5-Thia-1-Azabicyclo[4.2.0]Oct-2-En-8-One 1,3-Dioxoisoindolin-2-Yl 2-Phenylacetate 1,3-Diphenylpropan-1-One 1,4-Diazepan-5-One 1,4-Dihydroisoquinolin-3(2H)-One 1-(1H-Indazol-1-Yl)Ethan-1-One 1-(1H-Indol-1-Yl)Ethan-1-One 1-(1H-Indol-3-Yl)Ethan-1-One 1-(1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Ethan-1-One 1-(2-(Trifluoromethyl)Phenyl)Ethan-1-One 1-(2-Aminophenyl)Ethan-1-One 1-(2-Bromophenyl)Ethan-1-One 1-(2-Chlorophenyl)Ethan-1-One 1-(2-Fluorophenyl)Ethan-1-One 1-(2-Hydroxyphenyl)-2-Phenylethan-1-One 1-(2-Hydroxyphenyl)-3-Phenylprop-2-En-1-One 1-(2-Hydroxyphenyl)Ethan-1-One 1-(2-Iodophenyl)Ethan-1-One 1-(2-Methoxyphenyl)Ethan-1-One 1-(2-Nitrophenyl)Ethan-1-One 1-(3-(Benzyloxy)Phenyl)Ethan-1-One 1-(3-Aminophenyl)Ethan-1-One 1-(3-Chlorophenyl)Ethan-1-One 1-(3-Fluorophenyl)Ethan-1-One 1-(3-Hydroxyphenyl)Ethan-1-One 1-(3-Iodophenyl)Ethan-1-One 1-(3-Methoxy-2-Nitrophenyl)Ethan-1-One 1-(3-Methoxyphenyl)Ethan-1-One 1-(3-Nitrophenyl)Ethan-1-One 1-(3-Nitrophenyl)Propan-1-One 1-(4-(Benzyloxy)Phenyl)Ethan-1-One 1-(4-Fluorophenyl)Ethan-1-One 1-([1,1'-Biphenyl]-4-Yl)Ethan-1-One 1-(Benzofuran-2-Yl)Ethan-1-One 1-(Imidazo[1,2-A]Pyridin-3-Yl)Ethan-1-One 1-(M-Tolyl)Ethan-1-One 1-(Naphthalen-2-Yl)Ethan-1-One 1-(O-Tolyl)Ethan-1-One 1-(Piperidin-1-Yl)Ethan-1-One 1-(Pyrazin-2-Yl)Ethan-1-One 1-(Pyridin-2-Yl)Ethan-1-One 1-(Pyridin-3-Yl)Ethan-1-One 1-(Pyridin-4-Yl)Ethan-1-One 1-(Pyrimidin-2-Yl)Ethan-1-One 1-(Pyrimidin-4-Yl)Ethan-1-One 1-(Pyrrolidin-1-Yl)Ethan-1-One 1-(Thiazol-2-Yl)Ethan-1-One 1-(Thiophen-2-Yl)Ethan-1-One 1-Aminoanthracene-9,10-Dione 1-Benzylindoline-2,3-Dione 1-Benzylpiperidin-3-One 1-Chloroanthracene-9,10-Dione 1-Hydroxyanthracene-9,10-Dione 1-Methylpiperazin-2-One 1-Methylpyrrolidin-2-One 1-Phenylbutan-1-One 1-Phenylpentan-1-One 1-Phenylpiperidin-2-One 1-Phenylpropan-2-One 2,2,2-Trifluoro-1-Phenylethan-1-One 2,2-Dimethyl-1-Phenylpropan-1-One 2,2-Dimethyl-2H-Benzo[B][1,4]Oxazin-3(4H)-One 2,3,4,9-Tetrahydro-1H-Carbazol-1-One 2,3-Dihydrofuran-3-One 2,3-Dihydropyridin-2-One 2,5-Dichlorobenzoic Acid 2-Amino-1-(Pyrrolidin-1-Yl)Ethan-1-One 2-Benzalacetophenone 2-Benzoylbenzoic Acid 2-Chloro-1-Phenylethan-1-One 2-Chlorocyclohexa-2,5-Diene-1,4-Dione 2-Chloroquinazolin-4(3H)-One 2-Hydroxy-1,2-Diphenylethan-1-One 2-Hydroxy-1-Phenylethan-1-One 2-Hydroxycyclohexa-2,5-Diene-1,4-Dione 2-Hydroxyquinolin-4(1H)-One 2-Methoxycyclohexa-2,5-Diene-1,4-Dione 2-Methyl-1-Phenylpropan-1-One 2-Methyl-2H-Benzo[B][1,4]Oxazin-3(4H)-One 2-Methyl-3,4-Dihydroisoquinolin-1(2H)-One 2-Methylcyclohexa-2,5-Diene-1,4-Dione 2-Methylcyclohexan-1-One 2-Methylisoindolin-1-One 2-Methylisoindoline-1,3-Dione 2-Methylpyridazin-3(2H)-One 2-Oxo-2-Phenylacetaldehyde 2-Oxo-2-Phenylacetic Acid 3,3-Difluoropiperidin-4-One 3,3-Dimethylcyclohexan-1-One 3,3-Dimethylpiperidin-4-One 3,4-Dihydroquinoxalin-2(1H)-One 3-Acetyl-2H-Chromen-2-One 3-Aminopyrrolidin-2-One 3-Bromo-1H-Pyrrole-2,5-Dione 3-Chloro-1-Phenylpropan-1-One 3-Fluoropiperidin-4-One 3-Hydroxy-2-Phenyl-4H-Chromen-4-One 3-Hydroxypyrrolidin-2-One 3-Methylcyclohexan-1-One 3-Methylene-2,3-Dihydro-1H-Inden-1-One 3-Methylpiperazin-2-One 3-Methylpyrimidin-4(3H)-One 3-Oxo-3-Phenylpropanenitrile 3-Oxo-N-Phenylbutanamide 3-Phenyl-1-(Pyrrolidin-1-Yl)Propan-1-One 3-Phenyl-2-Thioxoimidazolidin-4-One 3-Phenylacrylaldehyde 3-Phenylimidazolidine-2,4-Dione 4,4,4-Trifluoro-1-Phenylbutane-1,3-Dione 4-(1,2,2-Triphenylvinyl)Benzaldehyde 4-(Hydroxymethyl)Pyrrolidin-2-One 4-Benzylmorpholin-3-One 4-Bromoisoindolin-1-One 4-Bromopyridazin-3(2H)-One 4-Chloro-1-Phenylbutan-1-One 4-Chloropyridazin-3(2H)-One 4-Fluoroindoline-2,3-Dione 4-Hydroxy-2H-Chromen-2-One 4-Hydroxydihydrofuran-2(3H)-One 4-Hydroxypiperidin-2-One 4-Hydroxypyrrolidin-2-One 4-Methyl-2H-Chromen-2-One 4-Methylisobenzofuran-1(3H)-One 4-Oxo-4-Phenylbutanoic Acid 4-Phenylbutan-2-One 4-Phenylcyclohexan-1-One 4-Phenylmorpholin-3-One 4-Phenylpyrrolidin-2-One 5,6-Dihydrobenzo[D]Thiazol-7(4H)-One 5-(Aminomethyl)Pyrrolidin-2-One 5-(Hydroxymethyl)Pyrrolidin-2-One 5-Bromoisoindolin-1-One 5-Bromoisoindoline-1,3-Dione 5-Bromopyrimidin-4(3H)-One 5-Chloroisoindoline-1,3-Dione 5-Chloropyrimidin-4(3H)-One 5-Chloropyrimidine-2,4(1H,3H)-Dione 5-Fluoro-3,4-Dihydronaphthalen-1(2H)-One 5-Fluorochroman-4-One 5-Fluoroindolin-2-One 5-Fluoroisoindolin-1-One 5-Fluoropyrimidin-4(3H)-One 5-Fluoropyrimidine-2,4(1H,3H)-Dione 5-Hydroxy-2-Phenyl-4H-Chromen-4-One 5-Hydroxypiperidin-2-One 5-Methoxy-2-Phenyl-4H-Chromen-4-One 5-Methyl-3,4-Dihydronaphthalen-1(2H)-One 5-Methylindolin-2-One 5-Oxopyrrolidine-2-Carboxylic Acid 6-Bromoisoindolin-1-One 6-Fluorochroman-4-One 6-Fluoroindoline-2,3-Dione 6-Fluoroisobenzofuran-1(3H)-One 6-Hydroxy-2,3-Dihydro-1H-Inden-1-One 6-Methoxy-2,3-Dihydro-1H-Inden-1-One 6-Methoxy-3,4-Dihydronaphthalen-1(2H)-One 6-Methoxyisoindolin-1-One 6-Methyl-2,3-Dihydro-1H-Inden-1-One 7,8-Dihydroquinolin-5(6H)-One 7-(Diethylamino)-2H-Chromen-2-One 7-Bromo-3,4-Dihydronaphthalen-1(2H)-One 7-Bromochroman-4-One 7-Bromoindoline-2,3-Dione 7-Bromoquinazolin-4(3H)-One 7-Chloro-3,4-Dihydronaphthalen-1(2H)-One 7-Fluorochroman-4-One 7-Fluoroindolin-2-One 7-Fluoroquinazolin-4(3H)-One 7-Hydroxy-2H-Chromen-2-One 7-Methoxy-2H-Chromen-2-One 7-Methoxy-3,4-Dihydronaphthalen-1(2H)-One 7-Methoxychroman-4-One 7-Methylindoline-2,3-Dione 8-Bromochroman-4-One 8-Fluoro-3,4-Dihydronaphthalen-1(2H)-One 8-Fluoroisoquinolin-1(2H)-One 8-Methylchroman-4-One Acetophenone Azepan-2-One Benzo[Cd]Indol-2(1H)-One Benzofuran-2(3H)-One Chroman-2-One Cyclobutanone Cyclohex-2-En-1-One Cyclohexane-1,3-Dione Cyclopent-2-En-1-One Cyclopentane-1,3-Dione Dihydro-2H-Pyran-2,6(3H)-Dione Dihydrofuran-2,5-Dione Dihydrofuran-3(2H)-One Dihydrothiophen-3(2H)-One Ethene-1,1-Diyldibenzene Ethyl 2-Oxo-2-Phenylacetate Ethyl 3-Oxo-3-Phenylpropanoate Furan-2(5H)-One Isoquinolin-1-Ol Methyl 3-Oxo-3-Phenylpropanoate Morpholin-3-One Phenyl(3-(Trifluoromethyl)Phenyl)Methanone Phenyl(M-Tolyl)Methanone Phenyl(P-Tolyl)Methanone Phenyl(Pyridin-3-Yl)Methanone Phenyl(Thiophen-2-Yl)Methanone Piperidine-2,4-Dione Propiophenone Pyrimidine-4,6(1H,5H)-Dione Tert-Butyl (2-Oxopiperidin-3-Yl)Carbamate Tert-Butyl (2-Oxopyrrolidin-3-Yl)Carbamate Tert-Butyl (3-Oxocyclohexyl)Carbamate Tert-Butyl (5-Oxopyrrolidin-3-Yl)Carbamate Tert-Butyl (6-Oxopiperidin-3-Yl)Carbamate Tert-Butyl 2-Oxopiperidine-1-Carboxylate Tert-Butyl 2-Oxopyrrolidine-1-Carboxylate Tert-Butyl 4-Oxopiperidine-1-Carboxylate Tetrahydropyrimidin-2(1H)-One

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2,2,2-Trichloro-Ethanone 2,2-Dihydroxy-Ethanone 2,2-Dimethylpropan-1-One 2-Amino-Ethanone 2-Bromoethanone 2-Chloroacetyl 2-Hydroxyethanone 2-Oxoacetaldehyde 2-Oxopropanoic Acid 3-(Dimethylamino)Prop-2-Enoyl 3-Buten-2-One 3-Chloro-1-Propanone 3-Oxo-Propanenitrile 3-Oxobutanamide 4,4,4-Trifluoro-1,3-Dione 4-Chloro-Butan-1-One 4-Oxo-Butanoic Acid 4-Oxobut-2-Enoic Acid 5-Oxo-Pentanoic Acid Acetylacetonate Acetylquinoline Benzofuran-One Benzoimidazol-One Benzophenone Benzorophenone Benzothiazole-Thione Benzoxazin-One Benzoxazol-One Benzoyl Bromindan-One Bromoethanone Butan-1-One Butan-2-One Butane-1,3-Dione Butanedione Butanedione Butanone Butanone Carbazol-One Carbonyl Cyanide Carbonyl-Phenyl-Boronic Acid Carbonyl-Phenyl-Boronic Acid/Ester Carbonyl-Phenyl-Boronic-Acid Chloro-Inden-One Chloro-One Chloroethanone Chloropropiophenone Chroman-One Chromanone Chromanone Chromen-One Dicarbonyl Dicarbonyl Dichloroacetophenone Dienone Diethanone Diethanone Difluoroacetophenone Dihydroxy-Chromen-One Dimethyl-Indanone Dimethylamino-Propan-1-One Dione Dioxobutanoate Dioxohexanoate Dioxopentanoate Dithione Dithione Enone Ethanone Ethyl 2,4-Dioxobutanoate Ethyl 2-Oxoacetate Ethyl 3-Oxopropanoate Fluoren-One Fluorobenzoyl Formylpiperazine Furan-One Heptanedionato Heptanedionato Hexafluoroacetylacetonato Hexan-1-One Hydroxyethanone Imidazolidin-One Imidazolidine-One Imidazopyridin-One Indanone Indazol-One Inden-One Indol-One Indolin-One Isonicotinoyl Isoquinolin-One Methoxy-Indanone Methyl 2,4-Dioxo-Butanoate Methyl 2-Oxoacetate Methyl 3-Oxopropanoate Methyl-Pyrazolone Morpholino-Methanone Morpholinone Naphthyridin-One Nicotinoyl-Chloride Oxadiazol-One Oxoacetaldehyde Oxoazepane Oxoazepane Oxochroman Oxopropionate Oxotetrahydro Pentan-1-One Phenyl-Chromen-One Phenyl-One Phthalazin-One Piperazin-One Piperidine-Methanone Piperidinone Prop-2-En-1-One Propan-1-One Propan-2-One Purin-One Pyran-One Pyrazin-One Pyrazol-One Pyrazolopyridin-One Pyridazin-One Pyridinone Pyrimidinone Pyrrolidinone Pyrrolopyridin-One Quinazolin-One Quinolinone Tetrahydropyran-One Tetraone Tetraone Thiazolidine-One Triazine-One Triazol-One Trifluoro-Ethanone Trifluoroacetophenone Trifluoroethanone Trifluoromethyl-Acetophenone Trifluoromethyl-Phenyl-One Trione

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